Why is more dificulted?

Why is more dificult a cap 5 lvl 5 infectec than the cap 6 llvl 3 infected

Can you please elaborate?

The infected missions gets harder for each one you do. The one in chapter 5 might have appeared later and thus being harder.
Otherwise it could just bad luck getting certain creeps that works well together making it harder.

Been told that loosing an infected mission actually reduces difficulty, but haven’t tried it myself

https://discourse.disneyheroesgame.com/t/infected-regions-are-just-too-hard/9737

If the Infected Area’s just too hard to beat, try the Battle-Retreat strategy. Basically, you waste 1 stamina in exchange of lowering the creeps’ level by 1.

Do the level, but retreat when the level starts. Do this until you’re content with the level and rarity of the creeps.

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